Combination dolutegravir/lamivudine (DTG/3TC), an INSTI and NRTI, was approved in 2019. It is the first two-drug, fixed-dose complete regimen for the treatment of HIV-1 infection in treatment-naive adult patients.
What is the name of the new ARV?
Health Minister Dr Zweli Mkhize has launched a new fixed-dose combination antiretroviral (ARV) treatment called tenofovir/lamivudine/dolutegravir, simply known as TLD.
What are the side effects of the new Arvs?
Other side effects from antiretroviral drugs can include:hypersensitivity or allergic reactions, with symptoms such as fever, nausea, and vomiting.bleeding.bone loss.heart disease.high blood sugar and diabetes.lactic acidosis (high lactic acid levels in the blood)kidney, liver, or pancreas damage.More items
How many types of ARVs are there?
There are six main types (classes) of antiretroviral drugs. Each class of drug attacks HIV in a different way. Generally, drugs from two (or sometimes three) classes are combined to ensure a powerful attack on HIV.
Can ARV be given in pregnancy?
Women may receive ARV drugs during pregnancy as part of potent combination regimens used to treat their HIV infection or as prophylaxis to prevent HIV infection in infants. ARV treatment for women benefits their health but also substantially reduces the risk of MTCT.
When should I start taking Arvs during pregnancy?
ARV treatment should be started on the day of diagnosis. If HIV is diagnosed early in pregnancy, the recommendation is to commence FDC only at 12 weeks if the mother is healthy and does not require ARV drugs for her own health.
Which ARV should be avoided during pregnancy?
Cobicistat-boosted ARV drugs (ATV, DRV, or EVG) are not recommended for use in pregnancy. As noted above, EVG, DRV, ATV, and COBI levels have been found to be significantly lower during the third trimester than during the postpartum period.
Can I be pregnant while on Arvs?
If you are a woman with HIV and intend to get pregnant, most antiretroviral drugs are considered safe during pregnancy. If you are currently on treatment, you will likely be advised to continue if you become pregnant as long as you have an undetectable viral load.
Can Arvs harm my unborn baby?
During your pregnancy and delivery, you should take antiretroviral drugs (used to treat or prevent HIV) to lower the risk of passing the infection to your baby – even if your HIV viral load is very low. If you and your baby do not take antiretroviral drugs, there is about a 1 in 4 chance that your baby will get HIV.